Guangdong Raynovent Biotech Co., Ltd. ("Raynovent") is a sino-foreign joint venture focused on developing and commercializing innovative therapies for respiratory and metabolic diseases. Founded in October 2018 and headquartered in Huangpu District, Guangzhou, Raynovent is a controlling subsidiary of A-share listed Guangdong Zhongsheng Pharmaceutical Co., Ltd.
Leveraging deep expertise in disease pathophysiology, Raynovent targets key conditions including influenza, COVID-19, avian flu, idiopathic pulmonary fibrosis (IPF), non-alcoholic steatohepatitis (NASH), type 2 diabetes, and weight management.
Key pipeline highlights:
Leritrelvir tablets: World’s first oral peptidomimetic monotherapy 3CL protease inhibitor for mild-to-moderate COVID-19, approved in 2023. Used alone without ritonavir, it minimizes drug interactions and offers safer treatment for high-risk patients versus Paxlovid.
Onradivir tablets: World’s first influenza PB2 inhibitor, approved in May 2025; pediatric/adolescent indication in Phase III trials.
ZSP1601: China’s first innovative drug approved for NASH clinical trials, currently in Phase IIb.
RAY1225: Proprietary long-acting GLP-1/GIP dual agonist for metabolic syndrome, now in Phase III trials.
Raynovent aims to deliver innovative solutions for global respiratory and metabolic diseases—especially viral and infectious conditions—and to become a science-driven biotech leader recognized both in China and worldwide.



Innovation & Excellence
Responsible & Courageous
Teamwork & Integrity
March, 2018 - Commences financing for respiratory and NASH innovative drugs pipeline.
September, 2018 - “Phase 1/2 Clinical Research of Category 1 Drug ZSP1601 for the treatment of Non-Alcoholic Steatohepatitis (NASH)” and “Phase 1/2 Clinical Research of Category 1 Drug ZSP1603 for the treatment of Idiopathic Pulmonary Fibrosis (IPF)” were selected as the Major New Drugs Innovation and Development Scheme by the National Science and Technology Major Projects.
October, 2018 - Established in Dongguan.
December, 2018 - Series A round of financing rasies $15.8 Million by reputable overseas investors, Southern Orchard Limited and Snow Owl, LLC.
March, 2019 - Initiates co-development of the innovative drug RCYM001 for treatment of NASH, with Wuxi AppTec.
March, 2019 - Completes Phase 1 clinical trial of ZSP1601, a first-in-class NASH drug candidate.
March, 2019 - Completes Phase 1 clinical trial of ZSP1273, first RNA rolymerase small molecule inhibitor approved by China for clinical trials.
June, 2019 - Completes Phase 1 clinical trial of ZSP1603, the Category 1 Drug for the treatment of IPF and malignant tumor.
June,2019 - Completes Series A financing of $20Million, with the follow-on funding by overseas investor BioTrack Capital Fund I,LP.
June, 2019 - Signs an agreement to build its headquarter in Futian Bio-Medicine International Industrial Park, Shenzhen-Hong Kong Science and Technology Innovation Cooperation Zone.
August, 2019 - Convenes the National Investigators Conference of Phase 2 clinical trial of ZSP1273 to treat Influenza A, and initiates Phase 2 clinical trial, with Academician Zhong Nanshan as the Principle Investigator (PI).
November, 2019 - ZSP0678, the Category 1 Drug for the treatment of NASH, enteres Phase 1 clinical trial with the dosing of the first patient in China.
November, 2019 - “Development and Research of Category 1 New Chemical Drug WXSH0078 for the treatment of NASH” and “Development and Research of Category 1 New Chemical Drug WXSH0038 for the treatment of NASH” were selected as the Major New Drugs Innovation and Development Scheme by the National Science and Technology Major Projects.
December, 2019 - ZSP1273, the RNA polymerase small molecule inhibitor, enteres Phase 2 clinical trial with the dosing of the first patient in China.
